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DanielLardy Posted February 20 Share Posted February 20 Many people who have been prescribed Prednisone may be familiar with the frustrating side effect of weight gain. It can be disheartening to see the numbers on the scale go up, especially when you're already dealing with the challenges of managing your health condition. But how long does it actually take to lose the weight gained from taking Prednisone? Quote Link to comment Share on other sites More sharing options...